Dr Paula Heister
Subject
College Position
College Teaching Associate in Medicine
Degrees and Honours

MA, MSc, DPhil (Oxon), MBBS (Lond)

Research Interests

I am a physician-scientist with a background in pharmacology. My particular interest is intracellular calcium signalling, with a focus on the role of calcium channels in health and disease. I also maintain an interest in medical ethics, and am a keen advocate for collaborations between the basic sciences, clinical sciences, and the arts and humanities.

Select Publications

Heister, P.M., Powell, T., Galione, A. Glucose and NAADP trigger elementary intracellular β-cell Ca2+ signals (2021). Sci Rep11(1):  10714.

Martin, J., Petrillo, A., Smyth, A.C., Shaida, N., Khwaja, S., Cheow, H.K., Duckworth,A., Heister, P.M., Praseedom, R., Jah,A., Balakrishnan, A., Harper, S., Liau,S., Kosmoliaptsis, V., Huguet, E. Colorectal liver metastases: current management and future perspectives (2020). World Journal of Clinical Oncology. 11(10): 761-808.

Heister, P.M., Poston, R. Pharmacological Hypothesis: TPC2 Antagonist Tetrandrine as a Potential Therapeutic Agent for COVID-19 (2020). Pharmacology Research & Perspectives. 8(5): e00653.

Maki, S., Kramarz, C., Heister, P.M., Pasha, K. First Presentation of Addison’s Disease as Hyperkalaemia in Acute Kidney Injury (2016). BMJ Case Rep. 11th May.

Arredouani, A., Ruas, M., Collins, S. C., Parkesh, R., Clough, F., Pillinger, T., Coltart, G., Rietdorf, K., Royle, A., Johnson, P., Braun, M., Zhang, Q., Sones, W., Shimomura, K., Morgan, A.J., Lewis, A.M., Chuang, K., Tunn, R., Gadea, J., Teboul, L., Heister, P.M., Tynan, P.W., Bellomo, E.A., Rutter, G.A., Rorsman, P., Churchill, G.C., Parrington, J., Galione, A. NAADP and endolysosomal two-pore channels modulate membrane excitability and stimulus-secretion coupling in mouse pancreatic β cells (2015). J. Biol. Chem. 290(35): 21376 - 92.